LOCUS       HSU90223                 960 bp    mRNA    linear   PRI 03-JAN-1998
DEFINITION  Human deoxyuridine triphosphate nucleotidohydrolase precursor mRNA,
            nuclear gene encoding mitochondrial protein, complete cds.
ACCESSION   U90223
VERSION     U90223.1  GI:2735291
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Ladner,R.D. and Caradonna,S.J.
  TITLE     The Human dUTPase Gene Encodes Both Nuclear and Mitochondrial
            Isoforms: Differential Expression of the Isoforms and
            Characterization of a cDNA Encoding the Mitochondrial Species
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Ladner,R.D. and Caradonna,S.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-1997) Dept. of Molecular Biology, Univ. of Med.
            and Dent. of NJ-School of Osteopathic Medicine, 2 Medical Center
            Drive, Stratford, NJ 08084, USA
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     CDS             63..821
                     /note="mitochondrial dUTPase isoform; DUT-M"
                     /codon_start=1
                     /product="deoxyuridine triphosphate nucleotidohydrolase
                     precursor"
                     /protein_id="AAB94642.1"
                     /db_xref="GI:2735292"
                     /translation="MTPLCPRPALCYHFLTSLLRSAMQNARGTAEGRSRGTLRARPAP
                     RPPAAQHGIPRPLSSAGRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSK
                     RARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQI
                     ALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIA
                     QLICERIFYPEIEEVQALDDTERGSGGFGSTGKN"
     sig_peptide     63..269
                     /note="mitochondrial targeting presequence"
     mat_peptide     270..818
                     /product="deoxyuridine triphosphate nucleotidohydrolase"
ORIGIN      
        1 ggtggaagcc tggcgcacgt ccggaggtgc cgaggaccca accagcccaa actctggggg
       61 aaatgactcc cctctgccct cgccccgcgc tctgctacca tttccttacg tctctgcttc
      121 gctcagcgat gcaaaacgcg cgaggcacgg cagagggccg aagccgcggt actctccggg
      181 ccaggcccgc ccctcggccg ccggcggcgc agcacgggat tccccggccg ctgtccagcg
      241 ctggccgcct gagccaaggc tgccgcggag ccagtacagt cggggccgct ggctggaagg
      301 gcgagcttcc taaggcgggg ggaagcccgg cgccggggcc ggagacaccc gccatttcac
      361 ccagtaagcg ggcccggcct gcggaggtgg gcggcatgca gctccgcttt gcccggctct
      421 ccgagcacgc cacggccccc acccggggct ccgcgcgcgc cgcgggctac gacctgtaca
      481 gtgcctatga ttacacaata ccacctatgg agaaagctgt tgtgaaaacg gacattcaga
      541 tagcgctccc ttctgggtgt tatggaagag tggctccacg gtcaggcttg gctgcaaaac
      601 actttattga tgtaggagct ggtgtcatag atgaagatta tagaggaaat gttggtgttg
      661 tactgtttaa ttttggcaaa gaaaagtttg aagtcaaaaa aggtgatcga attgcacagc
      721 tcatttgcga acggattttt tatccagaaa tagaagaagt tcaagccttg gatgacaccg
      781 aaaggggttc aggaggtttt ggttccactg gaaagaatta aaatttatgc caagaacaga
      841 aaacaagaag tcataccttt ttcttaaaaa aaaaaaaagt ttttgcttca agtgttttgg
      901 tgttttgcac ttctgtaaac ttactagctt taccttctaa aagtactgca ttttttactt
//